Menstrual Health
Online treatment for painful periods, irregular cycles, heavy bleeding, and PMS. Board-certified physicians prescribe hormonal therapy and evidence-based treatments. Same-day prescription.
Prescription required. Provider determines if clinically appropriate.
Menstrual health online — period & cycle care
Period pain (dysmenorrhea), heavy bleeding, and cycle irregularity are common and often treatable. First-line options include NSAIDs for cramping and hormonal therapy for cycle regulation or heavy bleeding. Some dysmenorrhea is caused by underlying conditions like endometriosis, fibroids, or PCOS that require workup. The FirstCall platform connects you with an independent, board-certified physician for evaluation and prescription, sent to a pharmacy of your choice.
NSAIDs, hormonal contraception, tranexamic acid for heavy bleeding
severe dysmenorrhea, sudden cycle changes, very heavy bleeding
endometriosis, fibroids, adenomyosis, PCOS, thyroid disease
Educational content. Last clinically reviewed by the FirstCall Clinical Editorial Board, June 2026. The FirstCall platform provides access to independent, licensed physicians; final clinical decisions rest with the prescribing physician. Seek emergency care for soaking a pad/hour for >2 hours, severe pelvic pain with fever, or fainting from blood loss.
Understanding painful and irregular periods
Understanding the condition makes the treatment decision clearer.
Dysmenorrhea (painful periods) affects the majority of women at some point. Primary dysmenorrhea has no underlying cause — it is driven by prostaglandins that trigger uterine contractions. Secondary dysmenorrhea is caused by conditions like endometriosis, fibroids, or PCOS. Menorrhagia (heavy bleeding) and cycle irregularity may have hormonal, structural, or thyroid-related causes. A physician consultation helps determine the right treatment approach for your specific pattern and symptoms.
Key insight: Painful periods are not something women have to accept as normal. Primary dysmenorrhea is highly treatable with prescription-strength NSAIDs and hormonal therapy. Secondary dysmenorrhea signals an underlying condition that deserves evaluation.
Painful periods are not something you have to accept
Dysmenorrhea is the leading cause of missed school and work among women. Yet fewer than 15% of women with significant menstrual pain seek treatment. Effective, prescription-strength treatment is available online, privately, and without a waiting room. A physician on the FirstCall platform can evaluate your symptom pattern and recommend appropriate treatment the same day.
What to expect
Set realistic expectations and stay consistent — results take time.
Prescription NSAIDs work within the first cycle. Hormonal treatments may take 2–3 cycles for full effect.
Significant reduction in cramping severity. Period flow typically lightens with hormonal treatment.
Cycles become more predictable and manageable with consistent treatment.
Continued treatment maintains symptom control throughout each cycle.
PMS and PMDD are medical conditions — not mood swings
Premenstrual syndrome (PMS) affects up to 75% of women. Premenstrual dysphoric disorder (PMDD) — a severe form causing significant mood disruption in the luteal phase — affects approximately 5%. Both are recognized medical conditions with effective treatments. SSRIs taken daily or only during the luteal phase significantly reduce PMDD symptoms. Hormonal therapy also helps. Your physician can evaluate whether your premenstrual symptoms warrant treatment.
The science behind menstrual health
Evidence-based treatment addresses the underlying mechanism — not just the symptoms.
Prescription-strength NSAIDs (ibuprofen, naproxen) taken at the onset of symptoms reduce prostaglandin production — directly addressing the mechanism of primary dysmenorrhea. More effective than OTC doses when taken as prescribed. Start at the first sign of cramps, not after pain is established.
Combined hormonal contraceptives reduce prostaglandin levels, thin the uterine lining, and typically lighten periods and reduce pain significantly. Progestin therapy can be used to regulate irregular cycles. The right hormonal approach depends on your contraceptive needs, health history, and symptom pattern.
Low-dose SSRIs for PMDD can be taken daily or only during the luteal phase (the 2 weeks before menstruation) — a unique dosing approach effective for cyclical mood symptoms. Combined with hormonal therapy for comprehensive relief. Your physician will assess your symptom timeline to determine the right approach.
Treatments that work together
Comprehensive care often combines complementary treatments for better outcomes.
Private consultation. No waiting room. Same-day care.
Your FirstCall consultation is HIPAA-protected and completely confidential. Describe your symptoms, menstrual pattern, and history online. A board-certified physician reviews and prescribes the same day. Medication ships in plain, unmarked packaging. Complete privacy from consultation to delivery.
How it works
From first visit to prescription in as little as 15 minutes.
Brief online health questionnaire from your phone. Takes 5–10 minutes.
A board-certified physician reviews privately and recommends your treatment — same day.
Sent to your pharmacy or shipped discreetly in plain, unmarked packaging.
Menstrual health treatment — affordable pricing
Free consultation. NSAIDs and hormonal therapy at competitive pricing.
How we’re different
FirstCall was built to make women’s health care genuinely accessible.
No 3-week appointment waitlists. Board-certified physicians prescribe the same day — often within the hour.
HIPAA-protected. Plain unmarked packaging. No waiting room, no front desk, no one who knows you.
One membership covers your whole household — women’s, men’s, senior care, and pets.
Trusted telehealth provider since 2017. Board-certified physicians licensed in your state.
*Based on publicly available competitor information.
Frequently asked questions
Clear answers about menstrual health and how FirstCall works.
Long-term high-dose NSAID use can affect kidney function and stomach lining — use as directed and with food. Hormonal therapies carry contraindications for women with certain cardiovascular conditions, blood clot history, or migraines with aura. SSRIs for PMDD require tapering if discontinued. Always disclose your full health history to your physician. Severe or sudden worsening of period pain warrants prompt medical evaluation to rule out acute conditions. Read full prescribing information ›
Related treatments
Other women’s health treatments available through FirstCall.






