TB-500 (Thymosin Beta-4)
A Thymosin Beta-4 fragment studied for soft-tissue recovery, flexibility, and inflammation modulation.
TB-500 is a synthetic fragment of Thymosin Beta-4, a protein involved in cell migration and tissue repair. It’s researched for recovery and mobility and is frequently paired with BPC-157 in recovery protocols.
Prescription required. Final clinical decisions rest with the prescribing physician.
What is TB-500 (Thymosin Beta-4)?
TB-500 is based on a region of Thymosin Beta-4, a naturally occurring protein that plays a role in cell migration, blood-vessel formation, and tissue repair. Research interest centers on its potential to support recovery of soft tissue and reduce inflammation following injury.
It’s often combined with BPC-157, which works through complementary mechanisms. TB-500 is not FDA-approved and is accessed through licensed compounding pharmacies under a physician’s prescription; FDA guidance on peptide compounding continues to evolve.
Potential benefits
Soft-tissue recovery
Studied for supporting recovery of muscle and connective tissue.
Flexibility & mobility
Often used in protocols aimed at range of motion and recovery.
Inflammation modulation
Examined for calming the inflammatory response after injury.
Pairs with BPC-157
Frequently stacked with BPC-157 for complementary recovery support.
How it works
How it’s taken
A subcutaneous injection on a cycle set by the prescribing physician; sometimes a loading phase followed by maintenance.
Typical protocol
Run in cycles with periodic reassessment; often paired with BPC-157 per physician protocol.
How ordering works
Complete the intake
Share your goals, health history, and current medications — about 5 minutes.
Physician evaluation
An independent, board-certified physician reviews your intake and, if appropriate, prescribes TB-500 (Thymosin Beta-4) with a dosing protocol.
Compounded & shipped
The prescription is filled by a licensed compounding pharmacy and shipped to your door with instructions.
What to know before TB-500 (Thymosin Beta-4)
TB-500 (Thymosin Beta-4) is a bioactive compound. The physician you’re connected with will review the relevant risks and contraindications for your situation before prescribing.
- •Injection-site reactions are the most commonly reported side effect.
- •Long-term human safety data is limited — most evidence is pre-clinical.
- •Disclose your full history; a history of cancer should be discussed before starting.
- •Source matters: gray-market “research only” peptides skip physician oversight and quality testing. FirstCall connects you with a licensed physician and a compounding pharmacy that follows USP standards.
TB-500 (Thymosin Beta-4) FAQ
What is TB-500 used for?
TB-500 is studied for soft-tissue recovery, flexibility, and inflammation. It’s used off-label under physician supervision and is not FDA-approved.
Is TB-500 FDA-approved?
No. It is prepared by licensed compounding pharmacies and prescribed off-label; FDA guidance on peptide compounding is evolving.
Why is TB-500 paired with BPC-157?
The two work through complementary mechanisms, so they’re frequently combined in recovery protocols. Your physician will advise whether a stack is appropriate.
How is it taken?
A subcutaneous injection on a cycle; the physician you’re connected with sets your dose and schedule.
How much does it cost?
TB-500 starts from $179/month. Final pricing is confirmed by the compounding pharmacy after your physician evaluation. The initial evaluation is free.
Ready to start TB-500 (Thymosin Beta-4)?
Complete a short medical intake — a supervising physician reviews it and, if appropriate, writes your prescription, and a licensed pharmacy ships to your door.
Pricing & regulatory note: The $179/mo price is an indicative starting point confirmed by the compounding pharmacy after physician evaluation. TB-500 (Thymosin Beta-4) is not an FDA-approved finished drug product; it is prepared by licensed compounding pharmacies and prescribed off-label. FDA guidance on peptide compounding continues to evolve and availability can change. A prescription is required.