Ipamorelin
A selective growth-hormone secretagogue — targeted GH release with minimal effect on cortisol or prolactin.
Ipamorelin is a ghrelin-receptor agonist that stimulates a clean, selective pulse of growth hormone. It’s valued for being one of the most targeted secretagogues, with little effect on cortisol, prolactin, or appetite.
Prescription required. Final clinical decisions rest with the prescribing physician.
What is Ipamorelin?
Ipamorelin mimics ghrelin to trigger growth-hormone release from the pituitary. Among GH secretagogues it’s considered notably selective — it raises GH without the cortisol, prolactin, or strong appetite effects seen with some older compounds.
It’s frequently paired with a GHRH analog like CJC-1295 for a complementary effect. Ipamorelin is accessed through licensed compounding pharmacies under physician prescription; it is not an FDA-approved finished product.
Potential benefits
Selective GH release
Targeted growth-hormone pulse with minimal impact on cortisol or prolactin.
Recovery support
Used in protocols aimed at recovery and lean body composition.
Sleep & well-being
GH release supports deep sleep and overall recovery.
Pairs with CJC-1295
Commonly combined with a GHRH analog for complementary GH stimulation.
How it works
How it’s taken
A small subcutaneous injection, often dosed at night and/or post-exercise per physician protocol; frequently combined with CJC-1295.
Typical protocol
Run in cycles with periodic reassessment; your physician sets the dose, timing, and whether to pair it with a GHRH analog.
How ordering works
Complete the intake
Share your goals, health history, and current medications — about 5 minutes.
Physician evaluation
An independent, board-certified physician reviews your intake and, if appropriate, prescribes Ipamorelin with a dosing protocol.
Compounded & shipped
The prescription is filled by a licensed compounding pharmacy and shipped to your door with instructions.
What to know before Ipamorelin
Ipamorelin is a bioactive compound. The physician you’re connected with will review the relevant risks and contraindications for your situation before prescribing.
- •Injection-site reactions are the most common side effect.
- •May cause mild water retention or head-rush/flushing shortly after dosing.
- •Active cancer or recent malignancy is a contraindication for GH-stimulating peptides.
- •Pregnancy and breastfeeding are contraindications for most peptides.
- •Source matters: gray-market “research only” peptides skip physician oversight and quality testing. FirstCall connects you with a licensed physician and a compounding pharmacy that follows USP standards.
Ipamorelin FAQ
What is Ipamorelin used for?
Ipamorelin is used to stimulate the body’s growth-hormone release for recovery and body composition. It’s prescribed off-label under physician supervision.
Is Ipamorelin FDA-approved?
No. It is prepared by licensed compounding pharmacies and prescribed off-label; it is not an FDA-approved finished drug product.
Why is Ipamorelin often paired with CJC-1295?
The two work through complementary pathways — CJC-1295 (a GHRH analog) plus Ipamorelin (a ghrelin-receptor agonist) can amplify GH release more than either alone.
How is it taken?
A small subcutaneous injection, dose and timing set by the physician you’re connected with.
How much does it cost?
Ipamorelin starts from $119/month. Final pricing is confirmed by the compounding pharmacy after your physician evaluation. The initial evaluation is free.
Ready to start Ipamorelin?
Complete a short medical intake — a supervising physician reviews it and, if appropriate, writes your prescription, and a licensed pharmacy ships to your door.
Pricing & regulatory note: The $119/mo price is an indicative starting point confirmed by the compounding pharmacy after physician evaluation. Ipamorelin is not an FDA-approved finished drug product; it is prepared by licensed compounding pharmacies and prescribed off-label. FDA guidance on peptide compounding continues to evolve and availability can change. A prescription is required.